Granulomas in the Liver, with a Focus on Infectious Causes

Eun-Young Karen Choi; Laura W Lamps

doi:10.1016/j.path.2018.02.008

Granulomas in the Liver, with a Focus on Infectious Causes

Surg Pathol Clin. 2018 Jun;11(2):231-250. doi: 10.1016/j.path.2018.02.008.

Authors

Eun-Young Karen Choi¹, Laura W Lamps²

Affiliations

¹ Department of Pathology, University of Michigan, University of Michigan, 5231B Medical Science I, 1301 Catherine Street, SPC 5602, Ann Arbor, MI 48109, USA. Electronic address: [email protected].
² Department of Pathology, University of Michigan, University of Michigan, 5231B Medical Science I, 1301 Catherine Street, SPC 5602, Ann Arbor, MI 48109, USA.

PMID: 29751872
DOI: 10.1016/j.path.2018.02.008

Abstract

Hepatic granulomas are encountered in approximately 2% to 10% of liver biopsies. There are many potential infectious and noninfectious causes; granulomas can be generally classified by their morphology, which may be helpful in refining the differential diagnosis. This article provides a review of hepatic granulomas with an emphasis on infectious causes.

Keywords: Granuloma; Granulomatous inflammation; Infection; Liver.

Publication types

Review

MeSH terms

Bacterial Infections / complications
Bacterial Infections / diagnosis
Bacterial Infections / pathology
Biopsy
Diagnosis, Differential
Granuloma / diagnosis
Granuloma / microbiology*
Granuloma / pathology
Humans
Liver / pathology
Liver Diseases / diagnosis
Liver Diseases / microbiology*
Liver Diseases / pathology
Mycoses / complications
Mycoses / diagnosis
Mycoses / pathology
Parasitic Diseases / complications
Parasitic Diseases / diagnosis
Parasitic Diseases / pathology
Virus Diseases / complications
Virus Diseases / diagnosis
Virus Diseases / pathology