Differentiation between Pure Mucinous Breast Carcinomas and Fibroadenomas with Strong High-Signal Intensity on T2-Weighted Images from Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Ning Qu; Yahong Luo; Tao Yu; Huihui Yu

doi:10.1159/000479955

Differentiation between Pure Mucinous Breast Carcinomas and Fibroadenomas with Strong High-Signal Intensity on T2-Weighted Images from Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Breast Care (Basel). 2018 Mar;13(1):32-37. doi: 10.1159/000479955. Epub 2017 Dec 13.

Authors

Ning Qu¹, Yahong Luo¹, Tao Yu¹, Huihui Yu²

Affiliations

¹ Department of Radiology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, China.
² Department of Epidemiology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, China.

Abstract

Objective: This study aimed to identify characteristics that can differentiate between pure mucinous breast carcinomas (PMBCs) and fibroadenomas (FAs) with strong high-signal intensity on T2-weighted images (T2-SHi) from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI).

Methods: The DCE-MRI tumor characteristics were compared and analyzed between 35 PMBCs and 70 FAs with T2-SHi.

Results: Multivariate analysis revealed that delayed enhancement pattern was the only significant independent predictor (p = 0.007).

Conclusion: A delayed enhancement pattern is the most reliable characteristic for differentiating PMBCs from FAs with T2-SHi from DCE-MRI.

Keywords: Breast cancers; Dynamic contrast-enhanced magnetic resonance imaging; Fibroadenoma; Pure mucinous breast carcinoma.