[FeFe]-Hydrogenase Mimetic Metallopolymers with Enhanced Catalytic Activity for Hydrogen Production in Water

Angew Chem Int Ed Engl. 2018 Sep 10;57(37):11898-11902. doi: 10.1002/anie.201804661. Epub 2018 Aug 19.

Abstract

Electrocatalytic [FeFe]-hydrogenase mimics for the hydrogen evolution reaction (HER) generally suffer from low activity, high overpotential, aggregation, oxygen sensitivity, and low solubility in water. By using atom-transfer radical polymerization (ATRP), a new class of [FeFe]-metallopolymers with precise molar mass, defined composition, and low polydispersity, has been prepared. The synthetic methodology introduced here allows facile variation of polymer composition to optimize the [FeFe] solubility, activity, and long-term chemical and aerobic stability. Water soluble functional metallopolymers facilitate electrocatalytic hydrogen production in neutral water with loadings as low as 2 ppm and operate at rates an order of magnitude faster than hydrogenases (2.5×105 s-1 ), and with low overpotential requirement. Furthermore, unlike the hydrogenases, these systems are insensitive to oxygen during catalysis, with turnover numbers on the order of 40 000 under both anaerobic and aerobic conditions.

Keywords: electrocatalysis; enzymes; hydrogen; metallopolymers; polymerization.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Biomimetic Materials / chemistry*
  • Biomimetic Materials / metabolism
  • Catalysis
  • Catalytic Domain
  • Coordination Complexes / chemistry*
  • Coordination Complexes / metabolism
  • Electrochemical Techniques
  • Electrodes
  • Hydrogen / chemistry*
  • Hydrogen / metabolism
  • Hydrogenase / chemistry
  • Hydrogenase / metabolism
  • Iron-Sulfur Proteins / chemistry
  • Iron-Sulfur Proteins / metabolism
  • Water / chemistry*

Substances

  • Coordination Complexes
  • Iron-Sulfur Proteins
  • Water
  • Hydrogen
  • iron hydrogenase
  • Hydrogenase