Atlas of axial spondyloarthritis in Spain 2017: Study design and population

Reumatol Clin (Engl Ed). 2019 May-Jun;15(3):127-132. doi: 10.1016/j.reuma.2018.08.003. Epub 2018 Oct 3.
[Article in English, Spanish]

Abstract

Objective: Atlas of Axial Spondyloarthritis in Spain 2017 aims to better understand the reality of the patients suffering from this disease from an integrated approach.

Methods: The Atlas 2017 based its results on an extensive cross-sectional patient survey conducted in Spain (2016), validated by a multidisciplinary group of experts on spondyloarthritis.

Results: Data from 680 patients with axSpA were obtained, most of them suffered from AS, were HLA-B27 positive, older than 45 years, and live as part of a couple. A large percentage had university studies, were disabled and members of a patient association. Patients reported a diagnostic delay of 8.5 years, high disease activity (BASDAI 5.5±2.2), moderate-important stiffness (61.0%), medium-high functional limitation (74.9%), and psychological distress (GHQ 5.7±4.5). A total of 54.7% reported taking NSAIDs, 28.4% DMARDs, 36.3% biological therapy and 32.2% were not receiving pharmacological treatment.

Conclusions: The Atlas survey data reveals still a long diagnostic delay, high disease activity, psychological distress, while an important proportion could be undertreated.

Keywords: Axial spondyloarthritis; Burden of disease; Carga de la enfermedad; Espondiloartritis axial; Gestión de la atención sanitaria; Healthcare management; Patient perspective; Perspectiva del paciente.

MeSH terms

  • Absenteeism
  • Adult
  • Aged
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Antirheumatic Agents / therapeutic use
  • Comorbidity
  • Cross-Sectional Studies
  • Delayed Diagnosis
  • Female
  • HLA-B27 Antigen / analysis
  • Humans
  • Male
  • Middle Aged
  • Severity of Illness Index
  • Socioeconomic Factors
  • Spain / epidemiology
  • Spondylarthritis / drug therapy
  • Spondylarthritis / economics
  • Spondylarthritis / epidemiology*
  • Spondylarthritis / psychology
  • Spondylitis, Ankylosing / drug therapy
  • Spondylitis, Ankylosing / epidemiology
  • Spondylitis, Ankylosing / genetics
  • Surveys and Questionnaires

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antirheumatic Agents
  • HLA-B27 Antigen