Seq-ing out the Killers of Mice and Men

Vincent Peng; Marina Cella

doi:10.1016/j.immuni.2018.11.007

Seq-ing out the Killers of Mice and Men

Immunity. 2018 Nov 20;49(5):793-795. doi: 10.1016/j.immuni.2018.11.007.

Authors

Vincent Peng¹, Marina Cella²

Affiliations

¹ Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA.
² Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA. Electronic address: [email protected].

PMID: 30462994
DOI: 10.1016/j.immuni.2018.11.007

Abstract

The diversity of natural killer cells between mouse and human is poorly understood. In this issue of Immunity, Crinier et al. (2018) utilize single-cell RNA-seq to profile splenic and blood NK cells from both organisms, uncovering both tissue- and species-specific transcriptomic signatures.

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Kommentar

MeSH terms

Humans
Immunity
Killer Cells, Natural*
Single-Cell Analysis*
Spleen