[Study of tumor-specific expression of some evolutionary new genes]

Vopr Onkol. 2016;62(3):495-500.
[Article in Russian]

Abstract

In this paper we have showed that evolutionary new genes DCD1(Dermicidin), LINC00309 (Long intergenic non-protein coding RNA 309) and CLLU1(Chronic lymphocytic leukemia up-regulated 1) have tumor-specific expression profile. Along with our previously published results this confirms the existence of the phenomenon of TSEEN (Tumor-Specifically Expressed, Evolutionarily Novel).

MeSH terms

  • Biomarkers, Tumor / genetics
  • Evolution, Molecular
  • Female
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Male
  • Neoplasm Proteins / genetics*
  • Neoplasms / classification
  • Neoplasms / genetics*
  • Neoplasms / pathology
  • Peptides / genetics*
  • RNA, Long Noncoding / genetics*

Substances

  • Biomarkers, Tumor
  • CLLU1 lncRNA, human
  • Neoplasm Proteins
  • Peptides
  • RNA, Long Noncoding
  • dermcidin