Plasmacytoma growth factor activity of murine granulocyte-macrophage colony-stimulating factor

J Immunol. 1988 Sep 15;141(6):1996-9.

Abstract

Mouse plasmacytoma FLOPC21 was adapted to culture in the presence of a mouse Th cell supernatant. A stable factor-dependent cell line was derived from this culture and the factor responsible for its growth was identified as granulocyte-macrophage colony-stimulating factor.

MeSH terms

  • Animals
  • Antibodies, Monoclonal / physiology
  • Cell Division / drug effects
  • Colony-Stimulating Factors / isolation & purification
  • Colony-Stimulating Factors / pharmacology
  • Colony-Stimulating Factors / physiology*
  • Granulocyte-Macrophage Colony-Stimulating Factor
  • Growth Substances / isolation & purification
  • Growth Substances / pharmacology
  • Growth Substances / physiology*
  • Interleukin-6
  • Interleukins / immunology
  • Interleukins / isolation & purification
  • Interleukins / physiology*
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Plasmacytoma / pathology*
  • Recombinant Proteins / pharmacology

Substances

  • Antibodies, Monoclonal
  • Colony-Stimulating Factors
  • Growth Substances
  • Interleukin-6
  • Interleukins
  • Recombinant Proteins
  • Granulocyte-Macrophage Colony-Stimulating Factor