Metachronous Isolated Splenic Metastasis in a Young Patient With Renal Cell Carcinoma: Case Report and Literature Review

Urology. 2019 May:127:13-18. doi: 10.1016/j.urology.2019.01.007. Epub 2019 Jan 16.

Abstract

Splenic metastasis is uncommon and is usually associated with widespread disease.1,2 Isolated splenic metastases from renal cancer are also rarer and are often an incidental finding. This eventuality may turn into a dangerous scenario due to a spontaneous splenic rupture leading to sudden death.2,3 At the best of our knowledge, only few cases of metastasis from renal cell carcinoma (RCC) have been documented in the literature.4-11 We hereby present a literature review of these cases and report a case of isolated splenic metastasis in a young man on active follow-up for a clear cell RCC clear cell Renal Cell Carcinoma (ccRCC).

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Biopsy, Needle
  • Carcinoma, Renal Cell / pathology*
  • Carcinoma, Renal Cell / surgery*
  • Fluorodeoxyglucose F18
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Laparoscopy / methods
  • Male
  • Neoplasms, Second Primary / diagnostic imaging*
  • Neoplasms, Second Primary / surgery*
  • Nephrectomy / methods
  • Positron Emission Tomography Computed Tomography / methods
  • Risk Assessment
  • Splenectomy / methods
  • Splenic Neoplasms / diagnostic imaging
  • Splenic Neoplasms / secondary
  • Splenic Neoplasms / surgery*
  • Time Factors
  • Treatment Outcome

Substances

  • Fluorodeoxyglucose F18