Electrochemical oxidative C-H/S-H cross-coupling between enamines and thiophenols with H2 evolution

Chem Sci. 2019 Jan 18;10(9):2791-2795. doi: 10.1039/c8sc05143g. eCollection 2019 Mar 7.

Abstract

Electrochemical oxidative C-H/S-H cross-coupling has been developed to construct the C-S bond in a highly straightforward and efficient manner. Various enamines and (hetero)aryl thiols could be transformed smoothly under undivided electrolytic cell conditions. Moreover, this electrosynthesis strategy not only avoided the use of chemical oxidants and transition metal catalysts, but also exhibited excellent atom economy.