Driving Pressure and Transpulmonary Pressure: How Do We Guide Safe Mechanical Ventilation?

Elizabeth C Williams; Gabriel C Motta-Ribeiro; Marcos F Vidal Melo

doi:10.1097/ALN.0000000000002731

Driving Pressure and Transpulmonary Pressure: How Do We Guide Safe Mechanical Ventilation?

Anesthesiology. 2019 Jul;131(1):155-163. doi: 10.1097/ALN.0000000000002731.

Authors

Elizabeth C Williams¹, Gabriel C Motta-Ribeiro, Marcos F Vidal Melo

Affiliation

¹ From the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts. Current Affiliation: Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland (E.C.W.).

Abstract

The physiological concept, pathophysiological implications and clinical relevance and application of driving pressure and transpulmonary pressure to prevent ventilator-induced lung injury are discussed.

Publication types

Research Support, N.I.H., Extramural
Review

MeSH terms

Humans
Positive-Pressure Respiration
Respiration, Artificial / methods*
Respiratory Mechanics / physiology*
Tidal Volume
Ventilator-Induced Lung Injury / prevention & control*

Abstract

Publication types

MeSH terms

Grants and funding