Early-Life Microbiota Perturbations and Behavioral Effects

Antonia P Francis; Maria Gloria Dominguez-Bello

doi:10.1016/j.tim.2019.04.004

Early-Life Microbiota Perturbations and Behavioral Effects

Trends Microbiol. 2019 Jul;27(7):567-569. doi: 10.1016/j.tim.2019.04.004. Epub 2019 May 15.

Authors

Antonia P Francis¹, Maria Gloria Dominguez-Bello²

Affiliations

¹ Department of Obstetrics and Gynecology, NYU Langone Health, New York, NY 10016, USA.
² Department of Biochemistry and Microbiology, Rutgers University, New Brunswick, NJ 08901, USA. Electronic address: [email protected].

PMID: 31103277
DOI: 10.1016/j.tim.2019.04.004

Abstract

The maternal environment, during the prenatal and postnatal periods, is a determinant of offspring development and health. Perturbations during these periods can affect maternal behaviors and maternal-infant bonding, and also impair transmission of maternal microbiota to the offspring. Impaired microbiota has been associated with alterations of offspring cognitive development and behavior.

Keywords: behavior; development; microbiota; offspring.

Publication types

Review

MeSH terms

Age Factors
Animals
Child Development
Host-Pathogen Interactions*
Humans
Infant
Microbial Interactions*
Microbiota*