Neuronal mechanisms underlying innate and learned olfactory processing in Drosophila

Hoger Amin; Andrew C Lin

doi:10.1016/j.cois.2019.06.003

Neuronal mechanisms underlying innate and learned olfactory processing in Drosophila

Curr Opin Insect Sci. 2019 Dec:36:9-17. doi: 10.1016/j.cois.2019.06.003. Epub 2019 Jun 8.

Authors

Hoger Amin¹, Andrew C Lin²

Affiliations

¹ Department of Biomedical Science, University of Sheffield, Firth Court, Western Bank, Sheffield, S10 2TN, United Kingdom.
² Department of Biomedical Science, University of Sheffield, Firth Court, Western Bank, Sheffield, S10 2TN, United Kingdom. Electronic address: [email protected].

PMID: 31280185
DOI: 10.1016/j.cois.2019.06.003

Abstract

Olfaction allows animals to adapt their behavior in response to different chemical cues in their environment. How does the brain efficiently discriminate different odors to drive appropriate behavior, and how does it flexibly assign value to odors to adjust behavior according to experience? This review traces neuronal mechanisms underlying these processes in adult Drosophila melanogaster from olfactory receptors to higher brain centers. We highlight neural circuit principles such as lateral inhibition, segregation and integration of olfactory channels, temporal accumulation of sensory evidence, and compartmentalized synaptic plasticity underlying associative memory.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Cues
Drosophila melanogaster / physiology*
Memory / physiology
Nervous System Physiological Phenomena*
Neuronal Plasticity
Neurons
Odorants
Smell*

Abstract

Publication types

MeSH terms

Grants and funding