Objective: To explore the hematological phenotype and genotype of hemoglobin Q-Thailand in Fujian area.
Methods: Genomic DNA was extracted from peripheral venous blood samples of patients. Suspected samples were screened by hematological parameters analysis and verified with DNA sequencing.
Results: In 35 patients suspected with Hb Q-Thailand, 20 were confirmed, which included one case compounded with heterozygous β CD41-42 mutation and one compounded with Hb New York.
Conclusion: Analysis of hematological phenotype and genotype of Hb Q-Thailand can faciliate genetic counseling for patients from Fujian area.