Asymptomatic pharyngeal carriage rate of Streptococcus pyogenes, its associated factors and antibiotic susceptibility pattern among school children in Hawassa town, southern Ethiopia

BMC Res Notes. 2019 Sep 10;12(1):564. doi: 10.1186/s13104-019-4601-9.

Abstract

Objectives: The aim of this study was to determine the asymptomatic pharyngeal carriage rate of S. pyogenes, antimicrobial pattern and related risk factors among school children in Hawassa, southern Ethiopia.

Results: Out of 287 school children's screened, 35 (12.2%) were colonized with S. pyogenes. The carriage rate was significantly associated with factors such as sex (female p = 0.013) occupational status of mother (p = 0.002), lower income source (500-900 ETB, 1000-1500 ETB) (p = 0.001, and p = 0.042), history of hospitalization (p = 0.00) and residence of the children (p = 0.002). High level resistant to tetracycline and low level to vancomycin were observed, while penicillin, amoxicillin, erythromycin, chloramphenicol, and ceftriaxone were found to be effective.

Keywords: Hawassa; Nasopharyngeal carriage; S. pyogenes.

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / therapeutic use*
  • Asymptomatic Infections / epidemiology
  • Carrier State / drug therapy*
  • Carrier State / epidemiology
  • Carrier State / microbiology
  • Child
  • Child, Preschool
  • Ethiopia / epidemiology
  • Female
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Pharynx / drug effects*
  • Pharynx / microbiology
  • Pneumococcal Infections / drug therapy*
  • Pneumococcal Infections / epidemiology
  • Pneumococcal Infections / microbiology
  • Schools
  • Sex Factors
  • Streptococcus pyogenes / drug effects*
  • Streptococcus pyogenes / physiology

Substances

  • Anti-Bacterial Agents