Osteoporosis in Rheumatic Diseases

Int J Mol Sci. 2019 Nov 22;20(23):5867. doi: 10.3390/ijms20235867.

Abstract

Osteoporosis is a chronic disease characterized by an increased risk of fragility fracture. Patients affected by rheumatic diseases are at greater risk of developing osteoporosis. The purpose of the present review is to discuss the pathogenesis, epidemiology, and treatment of osteoporosis in patients affected by rheumatic diseases with special focus for rheumatoid arthritis, psoriatic arthritis, spondyloarthritis, systemic lupus erythematosus, systemic sclerosis, vasculitides, Sjogren syndrome, and crystal-induced arthritis.

Keywords: arthritis; inflammation; osteoporosis; rheumatic diseases; rheumatology.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Osteoporosis* / epidemiology
  • Osteoporosis* / etiology
  • Osteoporosis* / therapy
  • Rheumatic Diseases* / complications
  • Rheumatic Diseases* / epidemiology
  • Rheumatic Diseases* / therapy