Abstract
Bioimaging has revolutionized modern medicine, and nanotechnology can offer further specific and sensitive imaging. We report here an amphiphilic dendrimer able to self-assemble into supramolecular nanomicelles for effective tumor detection using SPECT radioimaging. This highlights the promising potential of supramolecular dendrimer platforms for biomedical imaging.
MeSH terms
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Adenocarcinoma / diagnostic imaging
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Animals
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Cell Line, Tumor
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Chelating Agents / chemical synthesis
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Chelating Agents / chemistry
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Dendrimers / chemical synthesis
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Dendrimers / chemistry*
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Heterocyclic Compounds, 1-Ring / chemical synthesis
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Heterocyclic Compounds, 1-Ring / chemistry
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Humans
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Indium
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Indium Radioisotopes
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Mice
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Micelles
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Nanostructures / chemistry*
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Pancreatic Neoplasms / diagnostic imaging
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Radioisotopes
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Surface-Active Agents / chemical synthesis
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Surface-Active Agents / chemistry*
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Tomography, Emission-Computed, Single-Photon / methods
Substances
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Chelating Agents
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Dendrimers
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Heterocyclic Compounds, 1-Ring
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Indium Radioisotopes
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Indium-115
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Micelles
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Radioisotopes
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Surface-Active Agents
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Indium
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1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid
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Indium-111