Schrödinger's pipeline and the outsourcing of pharmaceutical innovation

Drug Discov Today. 2020 Mar;25(3):480-484. doi: 10.1016/j.drudis.2019.11.015. Epub 2019 Dec 10.

Abstract

In the wake of the Global Financial Crisis (2007-2008) cheaper, softer money flooded the worldwide markets. Faced with historically low capital costs, the pharmaceutical industry chose to pay down debt through share buybacks rather than invest in research and development (R&D). Instead, the industry explored new R&D models for open innovation, such as open-sourcing, crowd-sourcing, public-private partnerships, innovation centres, Science Parks, and the wholesale outsourcing of pharmaceutical R&D. However, economic Greater Fool Theory suggests that outsourcing R&D was never likely to increase innovation. Ten years on, the period of cheaper and softer money is coming to an end. So how are things looking? And what happens next?

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Crowdsourcing / trends
  • Drug Industry / economics*
  • Drug Industry / trends
  • Humans
  • Outsourced Services / economics*
  • Outsourced Services / trends
  • Public-Private Sector Partnerships / economics
  • Public-Private Sector Partnerships / trends
  • Research / economics*
  • Research / trends