A shared somatic translocation involving CUX1 in monozygotic twins as an early driver of AMKL in Down syndrome

Affiliations

• ¹ Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark. [email protected].
• ² Department of Clinical Genetics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. [email protected].
• ³ Department of Clinical Genetics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
• ⁴ Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
• ⁵ Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
• ⁶ Centre for Genomic Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
• ⁷ MRC MHU, BRC Hematology Theme, Oxford Biomedical Research Centre, Oxford Centre for Haematology, WIMM, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
• ⁸ Department of Haematology, Oxford University Hospitals NHS Trust, Oxford, UK.
• ⁹ Institute for Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark.