Non-tuberculosis Mycobacterium Tenosynovitis with Rice Bodies in a Patient with Systemic Lupus Erythematosus

Intern Med. 2020 Sep 15;59(18):2317-2320. doi: 10.2169/internalmedicine.4671-20. Epub 2020 Jun 15.

Abstract

Infectious disease with various presentations in systemic lupus erythematosus often resembles lupus flare. A 37-year-old woman presented with a swollen left index finger that had not resolved, despite 7 years of immunosuppressive treatment. MRI showed rice-body formation in the flexor tendon sheath and tenosynovectomy demonstrated chronic synovitis with epithelioid granuloma. A mycobacterial culture confirmed invasive mycobacterial tenosynovitis due to Mycobacterium chelonae. The patient was treated with moxifloxacin and clarithromycin and completely recovered.

Keywords: Mycobacterium chelonae; non-tuberculosis mycobacterium; rice-body formation; systemic lupus erythematosus; tenosynovitis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Clarithromycin / therapeutic use
  • Female
  • Fingers / microbiology*
  • Humans
  • Lupus Erythematosus, Systemic / complications*
  • Magnetic Resonance Imaging
  • Moxifloxacin / therapeutic use
  • Mycobacterium Infections / complications*
  • Mycobacterium Infections / microbiology
  • Symptom Flare Up
  • Tenosynovitis / complications*
  • Tenosynovitis / microbiology

Substances

  • Anti-Bacterial Agents
  • Clarithromycin
  • Moxifloxacin