New acetylenic metabolites from the toxic mushroom Tricholoma pardinum

Nat Prod Res. 2021 Dec;35(23):5081-5088. doi: 10.1080/14786419.2020.1777415. Epub 2020 Jun 15.

Abstract

Four unprecedented acetylenic alcohols, (Z)-non-7-en-5-yn-1,2,4-triol (1), (Z)-non-7-en-5-yn-1,4-diol (2), (Z)-1,2-dihydroxynon-7-en-5-yn-4-one (3), and (Z)-1-hydroxynon-7-en-5-yn-4-one (4) were isolated from the poisonous mushroom Tricholoma pardinum (Agaricales, Basidiomycota), together with the known compounds 1H-indole-3-carbaldehyde (5) and 6-hydroxy-1H-indole-3-carbaldehyde (6). Their structures were determined by NMR and IR spectroscopy, and mass spectrometry. The crude acetone extract of the mushroom showed potent anti-arthropod activity against Tetranychus urticae (Acarinae), a dangerous crop pest.[Figure: see text].

Keywords: Fungi; Tetranychus urticae; Tricholoma; acetylenic metabolites; anti-arthropod activity.

MeSH terms

  • Acetylene
  • Agaricales*
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Tricholoma*

Substances

  • Acetylene

Supplementary concepts

  • Tricholoma pardinum