Case of multisystem inflammatory syndrome in children presenting as fever and abdominal pain

Neha Mahajan; Huan Ting Chang; Rachel Leeman; Rachel Manalo; Wendy Robin Glaberson

doi:10.1136/bcr-2020-237306

Case of multisystem inflammatory syndrome in children presenting as fever and abdominal pain

BMJ Case Rep. 2020 Sep 8;13(9):e237306. doi: 10.1136/bcr-2020-237306.

Authors

Neha Mahajan¹, Huan Ting Chang¹, Rachel Leeman¹, Rachel Manalo¹, Wendy Robin Glaberson²

Affiliations

¹ Pediatrics, University of Miami, Miller School of Medicine, Miami, Florida, USA.
² Pediatrics, University of Miami, Miller School of Medicine, Miami, Florida, USA [email protected].

Abstract

This case aims to remind all providers to scrutinise for atypical presentations of multisystem inflammatory syndrome in children (MIS-C) which may mimic a more routine diagnosis. In the absence of mucocutaneous symptoms, the diagnosis of MIS-C can be missed. Given the potential for rapid deterioration of patients with MIS-C, early treatment and inpatient interventions are necessary.

Keywords: medical management; paediatric intensive care; tropical medicine (infectious disease).

Publication types

Case Reports

MeSH terms

Abdominal Pain / blood
Abdominal Pain / immunology*
Abdominal Pain / therapy
Abdominal Pain / virology
Adenosine Monophosphate / analogs & derivatives
Adenosine Monophosphate / therapeutic use
Alanine / analogs & derivatives
Alanine / therapeutic use
C-Reactive Protein / analysis
COVID-19 / blood
COVID-19 / diagnosis*
COVID-19 / immunology
COVID-19 / therapy
COVID-19 Drug Treatment
COVID-19 Nucleic Acid Testing
COVID-19 Serological Testing
Child
Diagnosis, Differential
Fever / blood
Fever / immunology*
Fever / therapy
Fever / virology
Humans
Interleukin 1 Receptor Antagonist Protein / therapeutic use
Intubation, Intratracheal
Male
Mucocutaneous Lymph Node Syndrome / diagnosis
Myocarditis / diagnosis
Nasopharynx / virology
Natriuretic Peptide, Brain / blood
SARS-CoV-2 / immunology
SARS-CoV-2 / isolation & purification*
Systemic Inflammatory Response Syndrome / blood
Systemic Inflammatory Response Syndrome / diagnosis*
Systemic Inflammatory Response Syndrome / immunology
Systemic Inflammatory Response Syndrome / therapy
Tachycardia / blood
Tachycardia / immunology*
Tachycardia / therapy
Tachycardia / virology
Treatment Outcome

Substances

Interleukin 1 Receptor Antagonist Protein
Natriuretic Peptide, Brain
remdesivir
Adenosine Monophosphate
C-Reactive Protein
Alanine

Supplementary concepts

pediatric multisystem inflammatory disease, COVID-19 related