Therapeutic antibodies and fusion inhibitors targeting the spike protein of SARS-CoV-2

Expert Opin Ther Targets. 2021 Jun;25(6):415-421. doi: 10.1080/14728222.2020.1820482. Epub 2020 Sep 17.
No abstract available

Keywords: N-terminal domain; S2 subunit; SARS-CoV-2; receptor-binding domain; spike protein; therapeutic targets.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Antibodies, Neutralizing / immunology
  • Antibodies, Neutralizing / therapeutic use*
  • Antiviral Agents / pharmacology*
  • Antiviral Agents / therapeutic use
  • COVID-19 / therapy*
  • COVID-19 / virology
  • COVID-19 Drug Treatment
  • Humans
  • SARS-CoV-2 / drug effects
  • SARS-CoV-2 / immunology*
  • Spike Glycoprotein, Coronavirus / drug effects*
  • Spike Glycoprotein, Coronavirus / immunology*
  • Virus Internalization / drug effects*

Substances

  • Antibodies, Neutralizing
  • Antiviral Agents
  • Spike Glycoprotein, Coronavirus
  • spike protein, SARS-CoV-2