Evaluation of continuous beam rescanning versus pulsed beam in pencil beam scanned proton therapy for lung tumours

Phys Med Biol. 2020 Dec 18;65(23):23NT01. doi: 10.1088/1361-6560/abc5c8.

Abstract

The treatment of moving targets with pencil beam scanned proton therapy (PBS-PT) may rely on rescanning strategies to smooth out motion induced dosimetric disturbances. PBS-PT machines, such as Proteus®Plus (PPlus) and Proteus®One (POne), deliver a continuous or a pulsed beam, respectively. In PPlus, scaled (or no) rescanning can be applied, while POne implies intrinsic 'rescanning' due to its pulsed delivery. We investigated the efficacy of these PBS-PT delivery types for the treatment of lung tumours. In general, clinically acceptable plans were achieved, and PPlus and POne showed similar effectiveness.

Publication types

  • Evaluation Study

MeSH terms

  • Carcinoma, Non-Small-Cell Lung / diagnostic imaging
  • Carcinoma, Non-Small-Cell Lung / pathology
  • Carcinoma, Non-Small-Cell Lung / radiotherapy*
  • Four-Dimensional Computed Tomography / methods*
  • Humans
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology
  • Lung Neoplasms / radiotherapy*
  • Movement
  • Proton Therapy / methods*
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted / methods*