Morphology and taxonomic status of Aedes aegypti populations across Senegal

PLoS One. 2020 Nov 18;15(11):e0242576. doi: 10.1371/journal.pone.0242576. eCollection 2020.

Abstract

Aedes aegypti is the primary vector of dengue, Zika, yellow fever and chikungunya viruses to humans. In Africa, two subspecies, Ae. aegypti aegypti (Aaa) and Ae. aegypti formosus (Aaf) have been described. Until very recently, it was considered that the two forms were sympatric in East Africa and that only Aaf was present in Central and West Africa. However, recent data suggests that Aaa was also common in Senegal without any clear evidence of genetic differences with Aaf. This study was carried out in different Ae. aegypti populations from Senegal to better clarify their taxonomic status. The larvae, pupae and eggs were collected between July and September 2018 and reared individually to adult stage. For each population, F1 progeny from eggs laid by a single female F0 were reared as sibling samples. The number of pale scales on the first abdominal tergite (T1) and the basal part of the second tergite (T2) were counted. Individuals with no pale scale on T1 were classified as Aaf while those with at least one pale scale on this tergite were classified as Aaa. The morphological variations within families of Aaf were studied across 4 generations. In total, 2400 individuals constituting 240 families were identified, of which 42.5% were heterogeneous (families with both forms). Multivariate statistical analysis of variance including T1 and T2 data together showed that populations were significantly different from each other. Statistical analysis of T1 alone showed a similarity between populations from the southeast while variations were observed within northwest population. The analysis of family composition across generations showed the presence of Aaa and Aaf forms in each generation. The classification of Ae. aegypti into two subspecies is invalid in Senegal. Populations exhibit morphological polymorphism at the intra-family level that could have biological and epidemiological impacts.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aedes / classification*
  • Aedes / pathogenicity
  • Aedes / virology*
  • Africa, Eastern
  • Africa, Western
  • Animals
  • Disease Vectors
  • Genetic Variation / genetics
  • Humans
  • Mosquito Vectors / classification
  • Mosquito Vectors / genetics*
  • Phylogeny
  • Senegal / epidemiology
  • Yellow Fever / epidemiology
  • Yellow Fever / genetics
  • Zika Virus / genetics
  • Zika Virus Infection / epidemiology
  • Zika Virus Infection / genetics

Grants and funding

This study was supported fully by H2020-INFRAIA-2016-2017 (INFRAVEC2) funds. There was no additional external funding received for this study.