Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018

Open Forum Infect Dis. 2020 Oct 16;7(11):ofaa493. doi: 10.1093/ofid/ofaa493. eCollection 2020 Nov.

Abstract

Rapid diagnostic tests (RDTs) for cholera are an important emerging tool for surveillance, yet the currently available tests have several limitations. We assess the performance of a new RDT, Cholkit, during a cholera outbreak in Malawi compared with culture and find a sensitivity of 93.0% (95% CI, 83.0%-98.1%) and a specificity of 95.7% (95% CI, 78.1%-100.0%).

Keywords: cholera; malawi; rapid test; vibrio cholerae.