Immunochromatographic test for the detection of SARS-CoV-2 in saliva

J Infect Chemother. 2021 Feb;27(2):384-386. doi: 10.1016/j.jiac.2020.11.016. Epub 2020 Dec 23.

Abstract

We evaluated the rapid immunochromatographic test for severe acute respiratory coronavirus 2 (SARS-CoV-2) antigen detection using 16 saliva specimens collected from 6 COVID-19 hospitalized patients, and detected N-antigen in 4 of 7 RT-PCR positive specimens. This POCT detected SARS-CoV-2 antigen in saliva and would be useful for COVID-19 diagnosis.

Keywords: Antigen test; COVID-19; Immunochromatography; POCT; SARS-CoV-2.

Publication types

  • Case Reports

MeSH terms

  • Antigens, Viral / analysis*
  • COVID-19 / diagnosis*
  • COVID-19 Serological Testing / methods*
  • Humans
  • Immunologic Tests
  • Nasopharynx / virology
  • Point-of-Care Testing
  • RNA, Viral / analysis
  • Reverse Transcriptase Polymerase Chain Reaction / methods
  • SARS-CoV-2 / immunology*
  • SARS-CoV-2 / isolation & purification
  • Saliva / virology*
  • Sensitivity and Specificity

Substances

  • Antigens, Viral
  • RNA, Viral