Breaking through the unknowns of the human reference genome

Nature. 2021 Feb;590(7845):217-218. doi: 10.1038/d41586-021-00293-8.

Abstract

Since the human genome was published in 2001, many of the gaps in the original sequence have been filled in, offering a more detailed understanding of genome regulation, structure and function.

Keywords: Genetics; Genomics; History.

Publication types

  • Historical Article
  • News

MeSH terms

  • Chromosomes, Human / genetics
  • DNA, Intergenic / genetics
  • Euchromatin / genetics
  • Genome, Human / genetics*
  • Genomics / standards*
  • Genomics / trends*
  • Haploidy
  • History, 21st Century
  • Human Genome Project / history
  • Humans
  • Proteins / genetics
  • Reference Standards
  • Repetitive Sequences, Nucleic Acid / genetics

Substances

  • DNA, Intergenic
  • Euchromatin
  • Proteins