Impact of the coronavirus disease 2019 pandemic on irritable bowel syndrome

J Gastroenterol Hepatol. 2021 Aug;36(8):2187-2197. doi: 10.1111/jgh.15466. Epub 2021 Mar 4.

Abstract

Background and aim: Gastrointestinal manifestations of the coronavirus disease 2019 (COVID-19) pandemic may mimic irritable bowel syndrome (IBS), and social distancing measures may affect IBS patients negatively. We aimed to study the impact of COVID-19 on respondents with self-reported IBS.

Methods: We conducted an anonymized survey from May to June 2020 in 33 countries. Knowledge, attitudes, and practices on personal hygiene and social distancing as well as psychological impact of COVID-19 were assessed. Statistical analysis was performed to determine differences in well-being and compliance to social distancing measures between respondents with and without self-reported IBS. Factors associated with improvement or worsening of IBS symptoms were evaluated.

Results: Out of 2704 respondents, 2024 (74.9%) did not have IBS, 305 (11.3%) had self-reported IBS, and 374 (13.8%) did not know what IBS was. Self-reported IBS respondents reported significantly worse emotional, social, and psychological well-being compared with non-IBS respondents and were less compliant to social distancing measures (28.2% vs 35.3%, P = 0.029); 61.6% reported no change, 26.6% reported improvement, and 11.8% reported worsening IBS symptoms. Higher proportion of respondents with no change in IBS symptoms were willing to practice social distancing indefinitely versus those who deteriorated (74.9% vs 51.4%, P = 0.016). In multivariate analysis, willingness to continue social distancing for another 2-3 weeks (vs longer period) was significantly associated with higher odds of worsening IBS.

Conclusion: Our study showed that self-reported IBS respondents had worse well-being and compliance to social distancing measures than non-IBS respondents. Future research will focus on occupational stress and dietary changes during COVID-19 that may influence IBS.

Keywords: COVID-19; IBS; Social distancing.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • COVID-19 / epidemiology*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Irritable Bowel Syndrome / epidemiology*
  • Male
  • Pandemics*
  • Patient Compliance*
  • Retrospective Studies
  • SARS-CoV-2*
  • Self Report*
  • Singapore / epidemiology
  • Surveys and Questionnaires