Confounding case of seromucinous hamartoma

BMJ Case Rep. 2021 Mar 15;14(3):e240460. doi: 10.1136/bcr-2020-240460.

Abstract

A 67-year-old man presented with progressive diplopia. On evaluation, he was noted to have bilateral palsies of cranial nerves III, IV and VI as well as a unilateral right true vocal fold paralysis. CT and MRI studies demonstrated a T2-bright left ethmoid mass with no evidence of bony erosion. Direct visualisation demonstrated a polypoid appearing mass of the left sphenoethmoid recess. Operative biopsy was pursued with final pathology demonstrating benign seromucinous hamartoma. Subsequent blood work demonstrated high titres of anti-acetylcholine receptor antibodies consistent with myasthenia gravis. The patient was started on pyridostigmine with improvement in his ocular cranial neuropathies.

Keywords: ear; neuromuscular disease; nose and throat/otolaryngology; pathology.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cranial Nerve Diseases*
  • Diplopia / etiology
  • Hamartoma* / diagnosis
  • Humans
  • Male
  • Myasthenia Gravis*
  • Pyridostigmine Bromide

Substances

  • Pyridostigmine Bromide