Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

Affiliations

• ¹ Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA. [email protected].
• ² Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA. [email protected].
• ³ Department of Medicine, Harvard Medical School, Boston, MA, USA. [email protected].
• ⁴ Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
• ⁵ Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
• ⁶ Department of Internal Medicine: Cardiology, University of Michigan, Ann Arbor, MI, USA.
• ⁷ Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
• ⁸ University of Maryland School of Medicine, Division of Endocrinology, Diabetes and Nutrition and Program for Personalized and Genomic Medicine, Baltimore, MD, USA.
• ⁹ Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
• ¹⁰ Department of Biostatistics, University of Washington, Seattle, WA, USA.
• ¹¹ Department of Medicine, Harvard Medical School, Boston, MA, USA.
• ¹² Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
• ¹³ Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
• ¹⁴ The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA.
• ¹⁵ Department of Genetics, Washington University in St. Louis, St. Louis, MO, USA.
• ¹⁶ The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, New York, NY, USA.
• ¹⁷ Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
• ¹⁸ Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
• ¹⁹ VA Palo Alto Health Care System, Palo Alto, CA, USA.
• ²⁰ Section of Cardiovascular Research, Baylor College of Medicine, Houston, TX, USA.
• ²¹ Houston Methodist Debakey Heart and Vascular Center, Houston, TX, USA.
• ²² Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
• ²³ Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
• ²⁴ Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
• ²⁵ Division of Endocrine and Metabolism, Tri-Service General Hospital Songshan branch, Taipei, Taiwan.
• ²⁶ Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
• ²⁷ Division of Cardiology, George Washington University School of Medicine and Healthcare Sciences, Washington, DC, USA.
• ²⁸ Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
• ²⁹ Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.
• ³⁰ Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.
• ³¹ Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.
• ³² Departments of Human Genetics and Biostatistics, University of Pittsburgh, Pittsburgh, Pittsburgh, PA, USA.
• ³³ Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
• ³⁴ Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
• ³⁵ Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA.
• ³⁶ Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
• ³⁷ Deans office, School of Public Health, University of Kentucky, Lexington, KY, USA.
• ³⁸ Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
• ³⁹ The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
• ⁴⁰ Psomagen. Inc. (formerly Macrogen USA), Rockville, MD, USA.
• ⁴¹ Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
• ⁴² Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
• ⁴³ Cardiac Arrhythmia Service and Cardiovascular Research Center Massachusetts General Hospital, Boston, MA, USA.
• ⁴⁴ Institute of Molecular Medicine, the University of Texas Health Science Center at Houston, Houston, TX, USA.
• ⁴⁵ Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-, Salem, NC, USA.
• ⁴⁶ Genomics Platform, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
• ⁴⁷ New York Genome Center, New York, NY, USA.
• ⁴⁸ Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
• ⁴⁹ Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, and Tulane University Translational Science Institute, Tulane University, New Orleans, LA, USA.
• ⁵⁰ Department of Public Health and General Practice, HUNT Research Centre, Norwegian University of Science and Technology, Levanger, Norway.
• ⁵¹ K. G. Jebsen Center for Genetic Epidemiology, Dept of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
• ⁵² Departments of Medicine (Medical Genetics) and Genome Sciences, University of Washington, Seattle, WA, USA.
• ⁵³ Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
• ⁵⁴ Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
• ⁵⁵ The Mindich Child Health and Development Institute, Ichan School of Medicine at Mount Sinai, New York, NY, USA.
• ⁵⁶ Illumina Laboratory Services, Illumina inc., San Diego, CA, USA.
• ⁵⁷ Department of Epidemiology and International Health Institute, Brown University, Providence, RI, USA.
• ⁵⁸ Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA.
• ⁵⁹ Department of Genome Sciences, University of Washington, Seattle, WA, USA.
• ⁶⁰ University of Washington Center for Mendelian Genomics, Seattle, WA, USA.
• ⁶¹ Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
• ⁶² Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
• ⁶³ Departments of Epidemiology and Health Services, University of Washington, Seattle, WA, USA.
• ⁶⁴ Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
• ⁶⁵ The Icelandic Heart Association, Kopavogur, Iceland.
• ⁶⁶ Departments of Pathology & Laboratory Medicine and Biochemistry, Larrner College of Medicine, University of Vermont, Colchester, VT, USA.
• ⁶⁷ Sections of Preventive Medicine and Epidemiology and Cardiology, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
• ⁶⁸ Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
• ⁶⁹ NHLBI Framingham Heart Study, Framingham, MA, USA.
• ⁷⁰ Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
• ⁷¹ Verve Therapeutics, Cambridge, MA, USA.
• ⁷² Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
• ⁷³ Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.
• ⁷⁴ Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
• ⁷⁵ Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
• ⁷⁶ Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA. [email protected].