Hair of the mouse: A skin bacteria "cocktail" gets follicles back on their feet

Cell Host Microbe. 2021 May 12;29(5):742-744. doi: 10.1016/j.chom.2021.04.011.

Abstract

Microbes can boost cutaneous immune defense and skin reparative capacity. However, mechanistic understanding, especially of the latter, remains sparse. In this issue of Cell Host & Microbe, Wang et al. (2021) shed light on this, demonstrating that bacteria contribute to hair follicle neogenesis after skin wounding via keratinocyte-intrinsic IL-1R1 signaling.

Publication types

  • Kommentar

MeSH terms

  • Animals
  • Bacteria
  • Hair Follicle*
  • Mice
  • Regeneration
  • Signal Transduction
  • Skin*