Emerging issues related to COVID-19 vaccination in patients with cancer

Oncol Ther. 2021 Dec;9(2):255-265. doi: 10.1007/s40487-021-00157-1. Epub 2021 Jun 16.

Abstract

Coronavirus disease 2019 (COVID-19) has resulted in millions of deaths globally. The pandemic has had a severe impact on oncology care and research. Patients with underlying cancer are more vulnerable to contracting COVID-19, and also have a more severe clinical course following the infection. The rollout of COVID-19 vaccines in many parts of the world has raised hopes of controlling the pandemic. In this editorial, the authors outline key characteristics of the currently approved COVID-19 vaccines, provide a brief overview of key emerging issues such as vaccine-induced immune thrombotic thrombocytopenia and SARS-CoV-2 variants of concern, and review the available data related to the efficacy and side effects of vaccinating patients with cancer.

Keywords: COVID-19; Cancer; Efficacy; SARS-CoV-2; Toxicity; Vaccine; Viral vector; mRNA.

Publication types

  • Editorial