Dual role of epoxide hydratase in both activation and inactivation of benzo(a)pyrene

Arch Toxicol. 1977 Dec 30;39(1-2):65-75. doi: 10.1007/BF00343276.
No abstract available

MeSH terms

  • Animals
  • Benzopyrenes / metabolism
  • Benzopyrenes / pharmacology*
  • Biotransformation
  • Epoxide Hydrolases / pharmacology*
  • Methylcholanthrene / pharmacology
  • Mice
  • Microsomes, Liver / metabolism
  • Mutagens*
  • Mutation / drug effects*
  • Phenobarbital / pharmacology
  • Salmonella typhimurium / drug effects

Substances

  • Benzopyrenes
  • Mutagens
  • Methylcholanthrene
  • Epoxide Hydrolases
  • Phenobarbital