Inactivation of electrophilic metabolites by glutathione S-transferases and limitation of the system due to subcellular localization

Arch Toxicol. 1977 Dec 30;39(1-2):87-96. doi: 10.1007/BF00343278.
No abstract available

MeSH terms

  • Animals
  • Benzopyrenes / metabolism*
  • Benzopyrenes / pharmacology
  • Biotransformation
  • Cytosol / metabolism
  • Glutathione / metabolism
  • Glutathione Transferase / metabolism*
  • Male
  • Mice
  • Microsomes, Liver / metabolism
  • Mutagens*
  • Salmonella typhimurium / drug effects

Substances

  • Benzopyrenes
  • Mutagens
  • Glutathione Transferase
  • Glutathione