An atypical cause of right lower abdominal pain: amoebiasis, a family cluster

Acta Gastroenterol Belg. 2021 Apr-Jun;84(2):362-364. doi: 10.51821/84.2.362.

Abstract

In this case report we present a family cluster of amoebiasis in a nonendemic region. A 46-year-old women, diagnosed with Crohn's disease for which she received no maintenance therapy, was evaluated for the suspicion of a flare. At colonoscopy however, atypical findings for Crohn's disease were seen. Histopathologic examination revealed micro-organisms compatible with amoebiasis. Interestingly, 4 years before this event she started a new relationship with a 38-year-old man who was diagnosed with liver-amoebiasis 3 months after the start of their relationship. On top of this, her 18-year-old daughter was diagnosed with amoebiasis 2 years after her diagnosis. The source of the infection remains unknown, but we speculate that the infection was transmitted feco-orally between the different members of this family. These cases illustrate that we should be aware of parasitological causes of colitis, especially in patients with atypical endoscopic images or when a close "relative" is diagnosed with amoebiasis.

Keywords: Amoebiasis; colitis; colonoscopy; inflammatory bowel disease; liver abscess.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain
  • Adolescent
  • Adult
  • Amebiasis*
  • Colitis*
  • Crohn Disease*
  • Dysentery, Amebic*
  • Female
  • Humans
  • Male
  • Middle Aged