FLT3-ITD signals bad news for core binding factor acute myeloid leukemia unless trisomy 22 comes to the rescue

Haematologica. 2022 Apr 1;107(4):783-784. doi: 10.3324/haematol.2021.279409.
No abstract available

Publication types

  • Kommentar

MeSH terms

  • Chromosomes, Human, Pair 22 / metabolism
  • Core Binding Factors
  • Humans
  • Leukemia, Myeloid, Acute* / diagnosis
  • Leukemia, Myeloid, Acute* / genetics
  • Leukemia, Myeloid, Acute* / metabolism
  • Mutation
  • Trisomy* / genetics
  • fms-Like Tyrosine Kinase 3 / genetics

Substances

  • Core Binding Factors
  • FLT3 protein, human
  • fms-Like Tyrosine Kinase 3

Supplementary concepts

  • Chromosome 22, trisomy