Long-Term Blood Pressure Variability Increases Risks of Dementia and Cognitive Decline: A Meta-Analysis of Longitudinal Studies

Hypertension. 2021 Sep;78(4):996-1004. doi: 10.1161/HYPERTENSIONAHA.121.17788. Epub 2021 Aug 15.

Authors

Pingping Jia¹, Helen W Y Lee¹, Joyce Y C Chan², Karen K L Yiu³, Kelvin K F Tsoi^{1

3}

Affiliations

¹ JC School of Public Health and Primary Care (P.J., H.W.Y.L., K.K.F.T.), The Chinese University of Hong Kong.
² Department of Medicine and Therapeutics, Faculty of Medicine (J.Y.C.C.), The Chinese University of Hong Kong.
³ Stanley Ho Big Data Decision Analytics Research Centre (K.K.L.Y., K.K.F.T.), The Chinese University of Hong Kong.

PMID: 34397274
DOI: 10.1161/HYPERTENSIONAHA.121.17788

Abstract

[Figure: see text].

Keywords: blood pressure; cognition; dementia; meta-analysis; risk factors.

Publication types

Meta-Analysis
Systematic Review

MeSH terms

Adult
Aged
Aged, 80 and over
Blood Pressure / physiology*
Cognitive Dysfunction / etiology*
Dementia / etiology*
Female
Humans
Hypertension / complications*
Hypertension / drug therapy
Hypertension / physiopathology
Longitudinal Studies
Male
Middle Aged