We used the BinaxNOW COVID-19 Ag Card to screen 1,540 asymptomatic college students for severe acute respiratory syndrome coronavirus 2 in a low-prevalence setting. Compared with reverse transcription PCR, BinaxNOW showed 20% overall sensitivity; among participants with culturable virus, sensitivity was 60%. BinaxNOW provides point-of-care screening but misses many infections.
Keywords: 2019 novel coronavirus disease; COVID-19; SARS-CoV-2; adolescents; antigen testing; asymptomatic; colleges; coronavirus disease; coronaviruses; institutions of higher education; respiratory infections; severe acute respiratory syndrome coronavirus 2; universities; viruses; young adults; zoonoses.