Deciphering the colonic fermentation characteristics of agavin and digestion-resistant maltodextrin in a simulated batch fermentation system

Int J Biol Macromol. 2021 Oct 31:189:151-159. doi: 10.1016/j.ijbiomac.2021.08.063. Epub 2021 Aug 14.

Abstract

Gut microbial fermentation of soluble dietary fibers promotes general and substrate-specific health benefits. In this study, the fermentation characteristics of two soluble branched-dietary fibers, namely, agavin (a type of agave fructans) and digestion-resistant maltodextrin (RD) were investigated against cellulose, using a simulated colonic fermenter apparatus employing a mixed culture of swine fecal bacteria. After 48 h of complete fermentation period, the microbial composition was different among all groups, where Bifidobacterium spp. and Lactobacillus spp. dominated the agavin treatment, while the members of the families Lachnospiraceae and Prevotellaceae dominated the RD treatment. Agavin treatment exhibited a clearly segregated two-phased prolonged fermentation trend compared to RD treatment as manifested by the fermentation rates. Further, the highest short-chain fatty acids production even at the end of the fermentation cycle, acidic pH, and the negligible concentration of ammonia accumulation demonstrated favorable fermentation attributes of agavin compared to RD. Therefore, agavin might be an effective and desirable substrate for the colonic microbiota than RD with reference to the expressed microbial taxa and fermentation attributes. This study revealed a notable significance of the structural differences of fermentable fibers on the subsequent fermentation characteristics.

Keywords: Agavin; Dietary fiber; Intestinal fermentation; Microbiota; Resistant dextrin; Short-chain fatty acid.

MeSH terms

  • Ammonia / analysis
  • Animals
  • Batch Cell Culture Techniques*
  • Bifidobacterium / growth & development
  • Biodiversity
  • Colon / physiology*
  • Colony Count, Microbial
  • Digestion
  • Fatty Acids, Volatile / metabolism
  • Fermentation*
  • Fructans / metabolism*
  • Hydrogen-Ion Concentration
  • Lactobacillus / growth & development
  • Microbiota
  • Nitrogen / analysis
  • Phylogeny
  • Polysaccharides / metabolism*
  • Swine
  • Time Factors

Substances

  • Fatty Acids, Volatile
  • Fructans
  • Polysaccharides
  • Ammonia
  • maltodextrin
  • Nitrogen