Recent Progress in the Synthesis of Heterocycles based on 1,3-diketones

Curr Org Synth. 2022 Mar 3;19(2):220-245. doi: 10.2174/1570179418666211011141428.

Abstract

N,O-heterocycles containing the dicarbonyl ring play a significant role in heterocyclic and therapeutic chemistry. Since the discovery of 1,3-diketones, numerous research works have been achieved regarding the synthesis and its chemical reactivity. In this review, we have described the most relevant publications involving β-diketone compounds published during the period between 2018 to date. In addition, we include the 1,3-diketones-based heterocyclic compounds prepared by various synthetic methodologies.

Keywords: 1; 3-diketones; dynthesis; heterocyclic compounds; multi-compound reaction; teactivity; therapeutic chemistry.

Publication types

  • Review

MeSH terms

  • Heterocyclic Compounds*
  • Ketones

Substances

  • Heterocyclic Compounds
  • Ketones