Emerging dynamics from high-resolution spatial numerical epidemics

Elife. 2021 Oct 15:10:e71417. doi: 10.7554/eLife.71417.

Abstract

Simulating nationwide realistic individual movements with a detailed geographical structure can help optimise public health policies. However, existing tools have limited resolution or can only account for a limited number of agents. We introduce Epidemap, a new framework that can capture the daily movement of more than 60 million people in a country at a building-level resolution in a realistic and computationally efficient way. By applying it to the case of an infectious disease spreading in France, we uncover hitherto neglected effects, such as the emergence of two distinct peaks in the daily number of cases or the importance of local density in the timing of arrival of the epidemic. Finally, we show that the importance of super-spreading events strongly varies over time.

Keywords: computational biology; epidemiology; global health; high perfomance computing; parallel computing; systems biology.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19 / epidemiology*
  • Communicable Diseases / epidemiology*
  • Epidemics / statistics & numerical data*
  • France / epidemiology
  • Geography / methods*
  • Humans
  • Public Health / instrumentation
  • Public Health / methods*
  • Spatial Analysis

Grants and funding

The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.