Efficacy of intravenous immunoglobulin in shrinking lung syndrome associated with mixed connective tissue disease: a case report

Clin Exp Rheumatol. 2022 May;40 Suppl 134(5):116-117. doi: 10.55563/clinexprheumatol/aotrf1. Epub 2022 Jan 24.

Abstract

Shrinking lung syndrome is a rare manifestation of connective tissue diseases, namely systemic lupus erythematosus. It is characterised by reduced lung volumes and extra-pulmonary restrictive ventilatory pattern with good response to high-dose glucocorticoids alone or in combination with a second immunosuppressive agent. Here, we describe a case associated with mixed connective tissue disease and effectively treated with intravenous immunoglobulin.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Lung / diagnostic imaging
  • Lung Diseases* / etiology
  • Lupus Erythematosus, Systemic* / complications
  • Lupus Erythematosus, Systemic* / diagnosis
  • Lupus Erythematosus, Systemic* / drug therapy
  • Mixed Connective Tissue Disease* / complications
  • Mixed Connective Tissue Disease* / drug therapy
  • Muscular Diseases*
  • Syndrome

Substances

  • Immunoglobulins, Intravenous