Need for standardized vancomycin dosing for coagulase-negative staphylococci in hospitalized infants

Eleanor J Harvey; Diane Ashiru-Oredope; Louise F Hill; Alicia Demirjian; United Kingdom Health Security Agency Staphylococcus capitis Incident Management Team

doi:10.1016/j.cmi.2022.09.016

Need for standardized vancomycin dosing for coagulase-negative staphylococci in hospitalized infants

Clin Microbiol Infect. 2023 Jan;29(1):10-12. doi: 10.1016/j.cmi.2022.09.016. Epub 2022 Oct 1.

Authors

Eleanor J Harvey¹, Diane Ashiru-Oredope², Louise F Hill³, Alicia Demirjian⁴; United Kingdom Health Security Agency Staphylococcus capitis Incident Management Team

Collaborators

United Kingdom Health Security Agency Staphylococcus capitis Incident Management Team:
Karthik Paranthaman, Elita Jauneikaite⁵, Yu Wan⁶, Russell Hope⁶, Andrew Robb⁷, Louise Thorn⁶, Paul Fleming⁸, Bruno Pichon⁶, Derren Ready⁶, Mustafa Elsayed⁹, Heather Felgate¹⁰, Ginny Moore¹¹, Santosh Pattnayak¹², Sakina Ali¹³, Ted Gasiorowski¹⁴, Timothy Watts¹⁵, Louise Wooster¹⁶, Vicky Payne¹⁷, Colin Brown⁶, Alleyna Claxton¹⁸, Christina Kortsalioudaki¹⁹, Mitul Patel²⁰, Nabeela Mughal²¹, Olga Moncayo²², Sujoy Banerjee²³, Liz McKechnie²⁴, Rashmi Gandhi²⁵, Rhys DCosta⁶, Minesh Khashu²⁶, Natasha Ratnaraja²⁷, Kavita Sethi²⁴, Simon Drysdale²⁸, Bharat Patel²⁹

Affiliations

¹ Healthcare-Associated Infection, Fungal, Antimicrobial Resistance, Antimicrobial Use & Sepsis Division, United Kingdom Health Security Agency, London, United Kingdom.
² Healthcare-Associated Infection, Fungal, Antimicrobial Resistance, Antimicrobial Use & Sepsis Division, United Kingdom Health Security Agency, London, United Kingdom; National Institute for Health and Care Research Health Protection Unit in Healthcare-Associated Infections and Antimicrobial Resistance, Imperial College, London, United Kingdom.
³ Centre for Neonatal and Paediatric Infection, Institute for Infection and Immunity, St George's, University of London, United Kingdom.
⁴ Healthcare-Associated Infection, Fungal, Antimicrobial Resistance, Antimicrobial Use & Sepsis Division, United Kingdom Health Security Agency, London, United Kingdom; National Institute for Health and Care Research Health Protection Unit in Healthcare-Associated Infections and Antimicrobial Resistance, Imperial College, London, United Kingdom; Department of Paediatric Infectious Diseases & Immunology, Evelina London Children's Hospital, Guy's and St. Thomas' National Health Service Foundation Trust, London, United Kingdom; Faculty of Life Sciences & Medicine, King's College London, United Kingdom. Electronic address: [email protected].
⁵ Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom.
⁶ HCAI, Fungal, AMR, AMU and Sepsis Division, UK Health Security Agency, London, United Kingdom.
⁷ Scottish Microbiology Reference Laboratories, Glasgow, United Kingdom.
⁸ Homerton University Hospital NHS Foundation Trust, London, United Kingdom.
⁹ Royal United Hospital, Bath NHS Foundation Trust, Bath, United Kingdom.
¹⁰ Quadram Institute BioScience, Norwich, United Kingdom.
¹¹ Research and Evaluation, UK Health Security Agency, Porton Down, Salisbury, United Kingdom.
¹² Medway NHS Foundation Trust, Kent, United Kingdom.
¹³ Luton and Dunstable Hospital, Bedfordshire Hospitals NHS Foundation Trust, Bedfordshire, United Kingdom.
¹⁴ St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
¹⁵ Evelina London Children's Hospital, London, United Kingdom.
¹⁶ Public Health Wales Microbiology, Sketty, United Kingdom.
¹⁷ University of Southampton Faculty of Environmental and Life Sciences School of Health Sciences, Southampton, United Kingdom.
¹⁸ Homerton Healthcare NHS Foundation Trust, London, United Kingdom.
¹⁹ University College London Hospital, London, United Kingdom.
²⁰ Birmingham Women's and Children's NHS Foundation Trust, Birmingham, United Kingdom.
²¹ Chelsea and Westminster Hospital, NHS Foundation Trust, London, United Kingdom.
²² Scottish Mycobacteria Reference Laboratory, NHS Lothian, Scotland.
²³ Swansea Bay University Health Board, Swansea, United Kingdom.
²⁴ Leeds Teaching Hospital NHS Trust, Leeds, United Kingdom.
²⁵ King's College Hospital, NHS Foundation Trust, London, United Kingdom.
²⁶ University Hospitals Dorset, Poole, United Kingdom.
²⁷ University Hospitals Coventry and Warwickshire NHS Trust, Coventry, United Kingdom.
²⁸ St George's University Hospital NHS Foundation Trust, London, United Kingdom.
²⁹ Public Health Laboratory London, Science Group, UK Health Security Agency, London, United Kingdom.

PMID: 36195185
DOI: 10.1016/j.cmi.2022.09.016

No abstract available

Keywords: Antibacterial; Glycopeptide; Hospital; Neonate; Paediatric.

MeSH terms

Anti-Bacterial Agents / therapeutic use
Coagulase
Humans
Infant
Microbial Sensitivity Tests
Staphylococcal Infections* / drug therapy
Staphylococcal Infections* / microbiology
Staphylococcus
Vancomycin* / therapeutic use

Substances

Vancomycin
Coagulase
Anti-Bacterial Agents