Risk factors and survival in patients with COVID-19 in northeastern Brazil

PLoS One. 2022 Nov 28;17(11):e0278213. doi: 10.1371/journal.pone.0278213. eCollection 2022.

Abstract

Background: Knowledge about the epidemiology and risk factors surrounding COVID-19 contributes to developing better health strategies to combat the disease.

Objective: This study aimed to establish a survival analysis and identify the risk factors for patients with COVID-19 in an upper middle-income city in Brazil.

Methods: A retrospective cohort study was conducted with 280 hospitalized patients with COVID-19. The eCOVID platform provided data to monitor COVID-19 cases and help the communication between professionals.

Results: Age ≥ 65 years was associated with decreased survival (54.8%), and females had a lower survival rate than males (p = 0.01). Regarding risk factors, urea concentration (p<0.001), hospital length of stay (p = 0.002), oxygen concentration (p = 0.005), and age (p = 0.02) were associated with death.

Conclusion: Age, hospital length of stay, high blood urea concentration, and low oxygen concentration were associated with death by COVID-19 in the studied population. These findings corroborate with studies conducted in research centers worldwide.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Brazil / epidemiology
  • COVID-19* / epidemiology
  • Female
  • Humans
  • Male
  • Oxygen
  • Retrospective Studies
  • Risk Factors

Substances

  • Oxygen

Grants and funding

Yes.This study was financed by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES) (Finance Code CAPES EPIDEMIAS 09/2020-grand/award number:23038.013745/2020-69 to H.A.B) and Fundação de Apoio à Pesquisa do Estado da Paraíba – Brasil (FAPESQ) (Finance Code COVID-19 003/2020). The funders The funders had role in study design, decision to publish and preparation of the manuscript.