Somatic TP53 mutations are preleukemic events in acute lymphoblastic leukemia

Blood. 2023 Mar 30;141(13):1640-1644. doi: 10.1182/blood.2022017249.

Guranda Chitadze^{1

2

3}, Anna Stengel⁴, Cathrin John-Klaua¹, Julien Bruckmüller^{1

5}, Heiko Trautmann^{1

2}, Michaela Kotrova^{1

2}, Franziska Darzentas^{1

2}, Miriam Kelm^{1

2}, Karol Pal^{1

6}, Nikos Darzentas^{1

2}, Lorenz Bastian^{1

2

3}, Britta Kehden^{1

2}, Wiebke Wessels^{1

2}, Aeint-Steffen Ströh^{1

2}, Hans-Heinrich Oberg⁷, Philipp M Altrock⁸, Constance Baer⁴, Manja Meggendorfer⁴, Nicola Gökbuget⁹, Claudia D Baldus^{1

2

3}, Claudia Haferlach⁴, Monika Brüggemann^{1

2

3}

¹ Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
² University Cancer Center Schleswig-Holstein, University Hospital Schleswig-Holstein, Kiel and Lübeck, Germany.
³ Clinical Research Unit CATCH-ALL, Christian-Albrechts-University of Kiel, Kiel, Germany.
⁴ Munich Leukemia Laboratory, Munich, Germany.
⁵ Solana Research GmbH, Windeby, Germany.
⁶ Central European Institute of Technology, Masaryk University, Brno, Czech Republic.
⁷ Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
⁸ Department of Evolutionary Theory, Max Planck Institute for Evolutionary Biology, Ploen, Germany.
⁹ Department of Medicine II, Goethe University Hospital, Frankfurt, Germany.

No abstract available

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