Stressing out over mucus secretion

Michael J Grey

doi:10.1016/j.chom.2023.02.005

Stressing out over mucus secretion

Cell Host Microbe. 2023 Mar 8;31(3):327-328. doi: 10.1016/j.chom.2023.02.005.

Author

Michael J Grey¹

Affiliation

¹ Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. Electronic address: [email protected].

Abstract

In this issue of Cell Host & Microbe, Naama et al. show that autophagy controls mucus secretion in the colons of mice. They demonstrate that autophagy reduces ER stress in mucus-producing goblet cells to enhance mucus production, which shapes the gut microbial community and protects against colitis.

MeSH terms

Animals
Colitis*
Goblet Cells
Intestinal Mucosa*
Mice
Mucus

Abstract

MeSH terms

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