Dismantling the tumoral cloak of self-protection

PLoS Biol. 2023 May 4;21(5):e3002104. doi: 10.1371/journal.pbio.3002104. eCollection 2023 May.

Abstract

Tumors protect themselves from immune clearance by promoting extramedullary hematopoiesis. A new study in PLOS Biology provides insights into the mechanisms underlying this process, which may hold the key to disrupting generation of the immunosuppressive tumor microenvironment.

Publication types

  • Kommentar

MeSH terms

  • Hematologic Diseases*
  • Hematopoiesis
  • Hematopoiesis, Extramedullary*
  • Humans
  • Interleukin-1alpha
  • Leukemia Inhibitory Factor
  • Neoplasms*
  • Tumor Microenvironment

Substances

  • Leukemia Inhibitory Factor
  • Interleukin-1alpha