The aging population is rising at record pace worldwide. Along with it, a steep increase in the prevalence of atrial fibrillation and heart failure with preserved ejection fraction is to be expected. Similarly, both atrial functional mitral and tricuspid regurgitation (AFMR and AFTR) are increasingly observed in daily clinical practice. This article summarizes all current evidence regarding the epidemiology, prognosis, pathophysiology, and therapeutic options. Specific attention is addressed to discern AFMR and AFTR from their ventricular counterparts, given their different pathophysiology and therapeutic needs.
Keywords: Atrial fibrillation; Atrial functional mitral regurgitation; Atrial functional tricuspid regurgitation; Atrial myopathy; Functional mitral regurgitation; Heart failure with preserved ejection fraction; Isolated tricuspid regurgitation; Left atrium.
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