Pseudomonas aeruginosa population genomics among adults with bronchiectasis across Germany

Ilona Rosenboom; Sibel Oguz; Idalina M Lüdemann; Felix C Ringshausen; Jessica Rademacher; Ludwig Sedlacek; Burkhard Tümmler; Nina Cramer

doi:10.1183/23120541.00156-2023

Pseudomonas aeruginosa population genomics among adults with bronchiectasis across Germany

ERJ Open Res. 2023 Jun 26;9(3):00156-2023. doi: 10.1183/23120541.00156-2023. eCollection 2023 May.

Authors

Ilona Rosenboom^{1

2}, Sibel Oguz¹, Idalina M Lüdemann^{1

2}, Felix C Ringshausen^{2

3

4

5}, Jessica Rademacher^{3

4}, Ludwig Sedlacek⁶, Burkhard Tümmler^{1

2

4}, Nina Cramer^{1

2}

Affiliations

¹ Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
² German Center for Infection Research (DZIF), Hannover, Germany.
³ Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
⁴ Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), German Center for Lung Research, Hannover, Germany.
⁵ European Reference Network for Rare and Complex Lung Diseases (ERN-LUNG), Frankfurt am Main, Germany.
⁶ Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.

Abstract

Genome sequencing of 130 Pseudomonas aeruginosa isolates from 110 bronchiectasis patients identified a few dominant clones common in the global bacterial population and numerous rare clones infrequently seen in the environment or other human infections https://bit.ly/3lIfD2X.