68 Ga-Prostate-Specific Membrane Antigen PET/CT in Imaging of Hemangiopericytoma

Jolanta Kunikowska; Beata E Chrapko

doi:10.1097/RLU.0000000000004769

68 Ga-Prostate-Specific Membrane Antigen PET/CT in Imaging of Hemangiopericytoma

Clin Nucl Med. 2023 Sep 1;48(9):e431-e433. doi: 10.1097/RLU.0000000000004769. Epub 2023 Jul 22.

Authors

Jolanta Kunikowska¹, Beata E Chrapko²

Affiliations

¹ From the Nuclear Medicine Department, Medical University of Warsaw, Warsaw.
² Department of Nuclear Medicine, Medical University of Lublin, Lublin, Poland.

PMID: 37482670
DOI: 10.1097/RLU.0000000000004769

Abstract

Hemangiopericytoma is a mesenchymal neoplasm that derives from pericytes surrounding the capillaries presenting overexpression of PSMA, which can be a source of pitfall in 68 Ga-PSMA-11 PET/CT. We reported 2 cases with recurrent hemangiopericytoma grade III with high expression of 68 Ga-PSMA-11 in PET/CT. Based on the performed examination, one of them received targeted α-therapy with the IV injection of 225 Ac-PSMA-617.

MeSH terms

Edetic Acid / metabolism
Gallium Radioisotopes
Hemangiopericytoma* / diagnostic imaging
Humans
Male
Positron Emission Tomography Computed Tomography / methods
Prostate / metabolism
Prostate-Specific Antigen / metabolism
Prostatic Neoplasms* / metabolism

Substances

Prostate-Specific Antigen
Gallium-68
Gallium Radioisotopes
Edetic Acid